Article
HLH-3 is a C. elegans Achaete/Scute protein required for differentiation of the hermaphrodite-specific motor neurons.
Mechanisms of development - 1 Jan 2000
Doonan Ryan, Hatzold Julia, Raut Saleel, Conradt Barbara, Alfonso Aixa
Abstract excerpt
Basic helix-loop-helix (bHLH) proteins of the Achaete/Scute (Ac/Sc) family are required for neurogenesis in both Drosophila and vertebrates. These transcription factors are commonly referred to as 'proneural' factors, as they promote neural fate in many contexts. Although Ac/Sc proteins have been studied in Hydra, jellyfish, many insects, and several vertebrates, the role of these proteins in Caenorhabditis...
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