Article
Cell-type specific regulation of serotonergic identity by the C. elegans LIM-homeodomain factor LIM-4.
Developmental biology - 15 Oct 2005
Zheng Xianwu, Chung Shinjae, Tanabe Takahiro, Sze Ji Ying
Abstract excerpt
How a common neurotransmitter phenotype specified in neurons of different origins is an outstanding issue in neuronal development and function. In C. elegans larvae, serotonin is synthesized in 2 pairs of neurons, the secretory neurons NSM and the chemosensory neurons ADF. In order to delineate the molecular mechanisms of serotonergic phenotype establishment, we have screened for neuron-specific serotonin...
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