Article
The consequence of low mannose-binding lectin plasma concentration in relation to susceptibility to Salmonella Infantis in chickens.
Veterinary immunology and immunopathology - 15 Jan 2015
Ulrich-Lynge Sofie L, Dalgaard Tina S, Norup Liselotte R, Kjærup Rikke M, Olsen John E, Sørensen Poul, Juul-Madsen Helle R
Abstract excerpt
Mannose-binding lectin (MBL) is a key protein in innate immunity. MBL binds to carbohydrates on the surface of pathogens, where it initiates complement activation via the lectin-dependent pathway or facilitates opsonophagocytosis. In vitro studies have shown that human MBL is able to bind to Salmonella, but knowledge in relation to chicken MBL and Salmonella is lacking. In order to study this relation day-old...
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