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Article

Siah: A Promising Anticancer Target

2 Mar 2013

Abstract excerpt

Siah ubiquitin ligases play important roles in a number of signaling pathways involved in the progression and spread of cancer in cell-based models, but their role in tumor progression remains controversial. Siah proteins have been described to be both oncogenic and tumor suppressive in a variety of patient cohort studies and animal cancer models. This review collates the current knowledge of Siah in cancer...

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PMID: 23455005
DOI: 10.1158/0008-5472.can-12-4348

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