Article
Evidence for diversifying selection in a set of Mycobacterium tuberculosis genes in response to antibiotic- and nonantibiotic-related pressure.
Molecular biology and evolution - 1 Jun 2013
Osório Nuno S, Rodrigues Fernando, Gagneux Sebastien, Pedrosa Jorge, Pinto-Carbó Marta, Castro António G, Young Douglas, Comas Iñaki, Saraiva Margarida
Abstract excerpt
Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculosis complex (MTBC), have allowed a better comprehension of its population structure and provided the foundation for molecular evolution analyses. These studies are crucial for a better understanding of TB, including...
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