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Article

In Host Mutational Adaptation of Mycobacterium Tuberculosis Complex Strains During Tuberculosis Infection.

The Journal of infectious diseases - 23 Sept 2026

Zhang Helen, Medina-Jaudes Naomi, Forcada-Nadal Alicia, Harrison Ewan M, Coll Francesc

Abstract excerpt

BACKGROUND: Tuberculosis (TB) is the leading cause of death from an infectious disease worldwide. Mutations arising in Mycobacterium tuberculosis complex (MTBC) strains during TB infection provide a record of bacterial adaptations, such as those needed to survive the attack of the immune system and antibiotic therapies. METHODS: We conducted a meta-analysis of MTBC sequenced strains with multiple isolates from...

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Topics

Mycobacterium tuberculosis
Humans
Mutation
Antitubercular Agents
Genome, Bacterial
Tuberculosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Drug Resistance, Bacterial

Adaptation, Physiological

Source

Open in PubMed Open full text

Identifiers

PMID: 42047497
DOI: 10.1093/infdis/jiag209
PMCID: PMC13600426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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