Article
Adolescent cannabis use increases risk for cocaine-induced paranoia.
Drug and alcohol dependence - 1 Mar 2010
Kalayasiri Rasmon, Gelernter Joel, Farrer Lindsay, Weiss Roger, Brady Kathleen, Gueorguieva Ralitza, Kranzler Henry R, Malison Robert T
Abstract excerpt
UNLABELLED: Cannabis can produce and/or exacerbate psychotic symptoms in vulnerable individuals. Early exposure to cannabis, particularly in combination with genetic factors, increases the risk of a subsequent, primary, psychotic disorder. Because paranoia is a common feature of stimulant abuse and cocaine-dependent individuals frequently endorse a history of cannabis abuse, we examined whether early cannabis...
Topics
- Adolescent
- Adolescent Behavior
- Age Factors
- Age of Onset
- Cannabis
- Catechol O-Methyltransferase
- Cocaine-Related Disorders
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Logistic Models
- Male
- Paranoid Disorders