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Article

Clonal diversity of recurrently mutated genes in myelodysplastic syndromes.

Leukemia - 1 Jun 2013

Walter M J, Shen D, Shao J, Ding L, White B S, Kandoth C, Miller C A, Niu B, McLellan M D, Dees N D, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, Link D C, DiPersio J F, Mardis E, Ley T J, Wilson R K, Graubert T A

Abstract excerpt

Recent studies suggest that most cases of myelodysplastic syndrome (MDS) are clonally heterogeneous, with a founding clone and multiple subclones. It is not known whether specific gene mutations typically occur in founding clones or subclones. We screened a panel of 94 candidate genes in a cohort of 157 patients with MDS or secondary acute myeloid leukemia (sAML). This included 150 cases with samples obtained at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23443460
DOI: 10.1038/leu.2013.58
PMCID: PMC3736571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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