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Article

Aplastic anemia and clonal evolution: germ line and somatic genetics

2 Dec 2016

Abstract excerpt

Clonal progression to myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) remains a dreaded complication for a subset of patients with bone marrow failure (BMF). Recognizing risk factors for the development of MDS or AML would inform individualized treatment decisions and identify patients who may benefit from early or upfront hematopoietic stem cell transplantation. Now that next-generation DNA...

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PMID: 27913465
DOI: 10.1182/asheducation-2016.1.74

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