Article
The Role of Mitochondrial DNA Mutations in Cardiovascular Diseases.
International journal of molecular sciences - 16 Jan 2022
Dabravolski Siarhei A, Khotina Victoria A, Sukhorukov Vasily N, Kalmykov Vladislav A, Mikhaleva Liudmila M, Orekhov Alexander N
Abstract excerpt
Cardiovascular diseases (CVD) are one of the leading causes of morbidity and mortality worldwide. mtDNA (mitochondrial DNA) mutations are known to participate in the development and progression of some CVD. Moreover, specific types of mitochondria-mediated CVD have been discovered, such as MIEH (maternally inherited essential hypertension) and maternally inherited CHD (coronary heart disease). Maternally...
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