Article
CACNA1C rs1006737 genotype and bipolar disorder: Focus on intermediate phenotypes and cardiovascular comorbidity.
Neuroscience and biobehavioral reviews - 1 Aug 2015
Ou Xiao, Crane David E, MacIntosh Bradley J, Young L Trevor, Arnold Paul, Ameis Stephanie, Goldstein Benjamin I
Abstract excerpt
Recently, multiple genome-wide association studies have identified a genetic polymorphism (CACNA1C rs1006737) that appears to confer susceptibility for BD. This article aims to summarize the existing literature regarding the impact of rs1006737 on functional and structural neuroimaging intermediate phenotypes. Twenty eight articles, representing 2486 healthy participants, 369 patients with BD and 104 healthy...
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