Article
The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls.
Journal of affective disorders - 1 Dec 2012
Soeiro-de-Souza Márcio Gerhardt, Otaduy Maria Concepción Garcia, Dias Carolina Zadres, Bio Danielle S, Machado-Vieira Rodrigo, Moreno Ricardo Alberto
Abstract excerpt
INTRODUCTION: Impairments in facial emotion recognition (FER) have been reported in bipolar disorder (BD) during all mood states. FER has been the focus of functional magnetic resonance imaging studies evaluating differential activation of limbic regions. Recently, the α1-C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene has been described as a risk gene for BD and its Met allele found to...
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