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Article

Variation in the CACNB2 gene is associated with functional connectivity of the Hippocampus in bipolar disorder

11 Feb 2019

Abstract excerpt

BACKGROUND: Calcium voltage-gated channel auxiliary subunit β2 is a protein that, in humans, is encoded by the CACNB2 gene. The β2 subunit is an auxiliary protein of voltage-gated calcium channels, which is predominantly expressed in hippocampal pyramidal neurons. A single-nucleotide polymorphism at the CACNB2 gene (rs11013860) has been reported in genome-wide association studies to be associated with bipolar...

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PMID: 30744588
DOI: 10.1186/s12888-019-2040-8

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