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XRCC1 and ERCC1 polymorphisms are related to susceptibility and survival of colorectal cancer in the Chinese population.

Mutagenesis - 1 May 2015

Dai Qiong, Luo Hua, Li Xing Pu, Huang Juan, Zhou Tie Jun, Yang Zhi-Hui

Abstract excerpt

Excision repair cross complementing group 1 (ERCC1) and X-ray repair cross-complementing groups 1 (XRCC1) are DNA repair enzymes. Polymorphisms in DNA repair genes may be important factors affecting cancer susceptibility, prognosis and therapy outcome. The purpose of this study was to investigate the correlation of ERCC1 and XRCC1 polymorphisms with colorectal cancer (CRC) risk, and explore the effect of...

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Source

Identifiers

PMID: 25690281
DOI: 10.1093/mutage/geu088

Genes

ERCC1
XRCC1

Provenance

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