Article
Association of ERCC1 Polymorphisms with the Risk of Colorectal Cancer: A Meta-Analysis.
Critical reviews in eukaryotic gene expression - 1 Jan 2017
Chen Jianfeng, Sun Ningjie, Hu Gang, Chen Xiansheng, Jiang Jiansong, Wu Haiming, Luo Gaojian
Abstract excerpt
The ERCC1 enzyme in the nucleotide excision repair (NER) pathway plays a vital role in DNA repair. Numerous epidemiological studies have evaluated the association between ERCC1 polymorphisms and the risk of colorectal cancer (CRC), with conflicting results. To evaluate the potential associations, we conducted a meta-analysis. Eligible studies were identified by searching electronic databases. The odds ratio (OR)...
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