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Genetic deletion of <i>gpr27</i> alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish

2 Dec 2019

Abstract excerpt

G protein-coupled receptors (GPCRs) comprise the largest group of membrane receptors in eukaryotic genomes and collectively they regulate nearly all cellular processes. Despite the widely recognized importance of this class of proteins, many GPCRs remain understudied. G protein-coupled receptor 27 (Gpr27) is an orphan GPCR that displays high conservation during vertebrate evolution. Although, GPR27 is known to be...

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PMID: 31914600
DOI: 10.1096/fj.201901466r

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