Article
Multiple binding sites for myogenic regulatory factors are required for expression of the acetylcholine receptor gamma-subunit gene.
The Journal of biological chemistry - 25 Oct 1991
Gilmour B P, Fanger G R, Newton C, Evans S M, Gardner P D
Abstract excerpt
The nicotinic acetylcholine receptor (AChR) is a critical component of the mechanism responsible for signal transduction between nerve and muscle. Induction of AChR gene expression occurs during myogenesis when myoblasts exit the cell cycle and fuse to form myotubes. Induction of muscle-specific genes during differentiation is believed to be mediated through the activities of members of the MyoD family of...
Topics
- Animals
- Base Sequence
- Binding Sites
- Cells, Cultured
- Chromosome Deletion
- DNA Fingerprinting
- DNA-Binding Proteins
- Gene Expression Regulation
- Mice
- Molecular Sequence Data
- Muscle Proteins