Article
Ouabain-resistant (Na+,K+)-ATPase enzyme activity in chemically induced ouabain-resistant C3H/10T1/2 cells.
Molecular toxicology - 1 Jan 2000
Shibuya M L, Miura T, Lillehaug J R, Farley R A, Landolph J R
Abstract excerpt
To further understand the molecular nature of changes leading to chemically induced ouabain resistance in C3H/10T1/2 Cl 8 (10T1/2) cells, we isolated plasma membranes from wild-type and ouabain-resistant (Ouar) 10T1/2 cells and characterized (Na,K)-ATPase activity in the plasma membrane fraction....
Topics
- Animals
- Blotting, Northern
- Cell Division
- Cell Line
- Cell Membrane
- Dose-Response Relationship, Drug
- Drug Resistance
- Enzyme Induction
- Hot Temperature
- Kinetics
- Mice
- Mutagenesis
- Nucleic Acid Probes
- Ouabain
- Phenotype
- Sodium-Potassium-Exchanging ATPase