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Article

Killing and mutation induction in quiescent V79 cells as influenced by nalidixic acid.

Mutation research - 1 Jan 1990

Ghosh R, Bhattacharjee S B

Abstract excerpt

Involvement of topoisomerase II in the repair of damage by N-methyl-N'-nitro-N-nitrosoguanidine, UV light and gamma-rays has been studied using quiescent V79 cells. In each case, the presence of nalidixic acid, the inhibitor of topoisomerase II, decreased the survival through suppression of potentially lethal damage repair. There was also an increase in the yield of mutants because of such suppression. The...

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Identifiers

PMID: 2153930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Killing and mutation induction in quiescent V79 cells as influenced by nalidixic acid.PMID 2153930Read ↗

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