Killing and mutation induction in quiescent V79 cells as influenced by nalidixic acid.

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Article

Killing and mutation induction in quiescent V79 cells as influenced by nalidixic acid.

Mutation research - 1 Jan 1990

Ghosh R, Bhattacharjee S B

Abstract excerpt

Involvement of topoisomerase II in the repair of damage by N-methyl-N'-nitro-N-nitrosoguanidine, UV light and gamma-rays has been studied using quiescent V79 cells. In each case, the presence of nalidixic acid, the inhibitor of topoisomerase II, decreased the survival through suppression of poten...

Topics

Animals
Cell Division
Cell Line
Cell Survival
Contact Inhibition
Cricetinae
Cricetulus
DNA Repair
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Drug Synergism
Gamma Rays
Methylnitronitrosoguanidine
Mutation
Nalidixic Acid
Radiation-Sensitizing Agents
Topoisomerase II Inhibitors
Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 2153930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2153930-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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