Article
Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2013
Pendergrass Sarah A, Verma Shefali S, Holzinger Emily R, Moore Carrie B, Wallace John, Dudek Scott M, Huggins Wayne, Kitchner Terrie, Waudby Carol, Berg Richard, McCarty Catherine A, Ritchie Marylyn D
Abstract excerpt
Investigating the association between biobank derived genomic data and the information of linked electronic health records (EHRs) is an emerging area of research for dissecting the architecture of complex human traits, where cases and controls for study are defined through the use of electronic phenotyping algorithms deployed in large EHR systems. For our study, 2580 cataract cases and 1367 controls were...
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