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Article

Uncovering genetic loci and biological pathways associated with age-related cataracts through GWAS meta-analysis.

Nature communications - 23 Oct 2024

Diaz-Torres Santiago, Lee Samantha Sze-Yee, García-Marín Luis M, Campos Adrian I, Lingham Garreth, Ong Jue-Sheng, Mackey David A, Burdon Kathryn P, Hunter Michael, Dong Xianjun, MacGregor Stuart, Gharahkhani Puya, Rentería Miguel E

Abstract excerpt

Age-related cataracts is a highly prevalent eye disorder that results in the clouding of the crystalline lens and is one of the leading causes of visual impairment and blindness. The disease is influenced by multiple factors including genetics, prolonged exposure to ultraviolet radiation, and a history of diabetes. However, the extent to which each of these factors contributes to the development of cataracts...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39438440
DOI: 10.1038/s41467-024-53212-6
PMCID: PMC11496520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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