Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of quercetin on P-glycoprotein transport ability in Chinese healthy subjects.

European journal of clinical nutrition - 1 Apr 2013

Wang S-Y, Duan K-M, Li Y, Mei Y, Sheng H, Liu H, Mei X, Ouyang W, Zhou H-H, Liu Z-Q

Abstract excerpt

OBJECTIVES: The aim of this study was to investigate the effect of quercetin on P-glycoprotein (P-gp) transport ability in vivo. SUBJECTS/METHODS: Genotype data were available from a total of 165 health volunteers. An open, randomized, two-period crossover clinical trial was performed in eighteen subjects with different MDR1 3435 C/T genotypes. All subjects took 500 mg quercetin or placebo daily from 1st to 13th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Body Mass Index

Share to Cross-Over Studies

Share to Dietary Supplements

Share to Propanolamines

Share to Quercetin

Source

Identifiers

PMID: 23422925
DOI: 10.1038/ejcn.2013.5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of quercetin on P-glycoprotein transport ability in Chinese healthy subjects.PMID 23422925Read ↗

Effect of quercetin on CYP3A activity in Chinese healthy participants.Semantic proximity Read ↗

Effects of curcumin on the pharmacokinetics of talinolol in human with ABCB1 polymorphism.Semantic proximity Read ↗

Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancerSemantic proximity Read ↗

Quercetin acts as a P-gp modulator via impeding signal transduction from nucleotide-binding domain to transmembrane domainSemantic proximity Read ↗

MDR1 genotype do not influence the absorption of a single oral dose of 100 mg talinolol in healthy Chinese males.Semantic proximity Read ↗

Quercetin significantly inhibits the metabolism of caffeine, a substrate of cytochrome P450 1A2 unrelated to CYP1A2*1C (-2964G>A) and *1F (734C>A) gene polymorphisms.Semantic proximity Read ↗

No sex difference in overall P-glycoprotein activity as assessed by talinolol disposition in humans.Semantic proximity Read ↗

Insights into Intestinal P-glycoprotein Function using Talinolol: A PBPK Modeling ApproachSemantic proximity Read ↗

Flavonoids as P-glycoprotein inhibitors for multidrug resistance in cancer: an in-silico approachSemantic proximity Read ↗

Flavonoids As CYP3A4 Inhibitors In VitroSemantic proximity Read ↗

Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.Semantic proximity Read ↗

Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.