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Insights into Intestinal P-glycoprotein Function using Talinolol: A PBPK Modeling Approach

2023-11-22

Abstract excerpt

<h4>ABSTRACT</h4> Talinolol is a cardioselective beta-blocker that was previously used to treat heart failure and myocardial infarction. Following the development of new, more effective beta-blockers with better study results, talinolol is now only used clinically for the treatment of arterial hypertension. In basic science, talinolol continues to be used as a test substance due to its pharmacokinetics. Its intes...

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Literature Corpus work
8adbfa47-ce9e-55e8-9c49-1ce428b250f7
DOI
10.1101/2023.11.21.568168
Open publication

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Insights into Intestinal P-glycoprotein Function using Talinolol: A PBPK Modeling ApproachDOI 10.1101/2023.11.21.568168
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