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Article

Effects of curcumin on the pharmacokinetics of talinolol in human with ABCB1 polymorphism.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Dec 2012

He X, Mo L, Li Z-Y, Tan Z-R, Chen Y, Ouyang D-S

Abstract excerpt

This study was to investigate the effect of concomitantly administered curcumin on the pharmacokinetics of talinolol and association with ABCB1 C3435T genetic polymorphism. A two-phase, randomized, single-blind, crossover study was carried out in 18 healthy male volunteers with different genotypes of ABCB1, including C3435C (CC, n = 6), C3435T (CT, n = 6) and T3435T (TT, n = 6). The pharmacokinetics of talinolol...

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Identifiers

PMID: 22725663
DOI: 10.3109/00498254.2012.697590

Genes

ABCB1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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