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Article

MDR1 genotype do not influence the absorption of a single oral dose of 100 mg talinolol in healthy Chinese males.

Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2005

Zhang Wei-Xia, Chen Guo-Lin, Zhang Wei, Tan Zhi-Rong, Liu Jie, Zhou Gan, Hu Dong-Li, Zhou Hong-Hao

Abstract excerpt

OBJECTIVE: We investigated the linkage between SNPs in exon 12 (C1236T), exon 21 (G2677T/A) and exon 26 (C3435T) of MDR1, and explored the effect of linked polymorphism on the absorption of talinolol after a single oral dose of 100 mg. METHODS: The genotype of 192 healthy Chinese volunteers was determined using PCR-RFLP with respect to the MDR1 alleles of interest, C1236T, G2677T/A and C3435T. Linkage...

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PMID: 16170863
DOI: 10.1016/j.cccn.2005.03.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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