Article

Full epistatic interaction maps retrieve part of missing heritability and improve phenotypic prediction

2022-07-21

Abstract excerpt

The first Genome Wide Association Studies (GWAS) shed light on the concept of missing heritability. It constitutes a mystery with transcending consequences from plant to human genetics. This mystery lies in the fact that a large proportion of phenotypes are not explained by unique or simple genomic modifications. One has to invoke genetic interactions among different loci, also known as epistasis, to partly accoun...

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Literature Corpus work: 4c6e5c77-3878-52fb-9c3b-6dcfd15ae969
DOI: 10.1101/2022.07.20.500572

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