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Article

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress.

The Biochemical journal - 1 May 2013

Salabei Joshua K, Cummins Timothy D, Singh Mahavir, Jones Steven P, Bhatnagar Aruni, Hill Bradford G

Abstract excerpt

Vascular injury and chronic arterial diseases result in exposure of VSMCs (vascular smooth muscle cells) to increased concentrations of growth factors. The mechanisms by which growth factors trigger VSMC phenotype transitions remain unclear. Because cellular reprogramming initiated by growth factors requires not only the induction of genes involved in cell proliferation, but also the removal of contractile...

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Identifiers

PMID: 23421427
DOI: 10.1042/BJ20121344
PMCID: PMC4040966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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