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Article

Is Parkinson disease associated with lysosomal integral membrane protein type-2?: challenges in interpreting association data.

Molecular genetics and metabolism - 1 Apr 2013

Maniwang Emerson, Tayebi Nahid, Sidransky Ellen

Abstract excerpt

Several genetic risk factors have been identified for Parkinson disease (PD), including mutations in glucocerebrosidase (GBA1). Recently, two single nucleotide polymorphisms (SNPs) described as SCARB2 SNPs were reported to be associated with PD. SCARB2 is an attractive candidate gene for PD as it encodes for lysosomal integral membrane protein type 2 (LIMP-2), a protein involved in transporting glucocerebrosidase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23419877
DOI: 10.1016/j.ymgme.2013.01.012
PMCID: PMC3606890

Genes

SCARB2
GBA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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