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Article

Evidence of an association between the scavenger receptor class B member 2 gene and Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2012

Michelakakis Helen, Xiromerisiou Georgia, Dardiotis Efthimios, Bozi Maria, Vassilatis Demetrios, Kountra Persa-Maria, Patramani Gianna, Moraitou Marina, Papadimitriou Dimitra, Stamboulis Eleftherios, Stefanis Leonidas, Zintzaras Elias, Hadjigeorgiou Georgios M

Abstract excerpt

Lysosomal protein 2 (LIMP2), the product of the scavenger receptor class B member 2 (SCARB2) gene, is a ubiquitously expressed transmembrane protein that is the mannose-6-phosphate-independent receptor for glucocerebrosidase (β-GCase); a deficiency in this protein causes Gaucher disease. Several studies have shown a link between mutations in the β-GCase gene and diseases characterized clinically by Parkinsonism...

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Source

Identifiers

PMID: 22223122
DOI: 10.1002/mds.24886

Genes

SCARB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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