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Article

DLG2, but not TMEM229B, GPNMB, and ITGA8 polymorphism, is associated with Parkinson's disease in a Taiwanese population.

Neurobiology of aging - 1 Apr 2018

Wu Hsiu-Chuan, Chen Chiung-Mei, Chen Yi-Chun, Fung Hon-Chung, Chang Kuo-Hsuan, Wu Yih-Ru

Abstract excerpt

Transmembrane or membrane-associated protein dysfunction is increasingly recognized as an important mechanism of pathogenesis in Parkinson's disease (PD). Previous genome-wide association studies and their meta-analysis in PD genes have identified several risk foci in transmembrane protein-encoding genes. Herein, we investigated the effect of 4 such PD-associated genetic variants reported in Caucasians, including...

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Source

Identifiers

PMID: 29290481
DOI: 10.1016/j.neurobiolaging.2017.11.016

Genes

DLG2
GPNMB
ITGA8

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