Article
LINGO-2 polymorphism and the risk of Parkinson's disease in Taiwan.
Parkinsonism & related disorders - 1 Jun 2012
Su Feng-Chieh, Chen Chiung-Mei, Chen Yi-Chun, Wu Yih-Ru
Abstract excerpt
''Leucine-rich repeat (LRR) and immunoglobulin (Ig) domain containing, Nogo receptor-interacting protein-1'' also known as LINGO-1 is a protein encoded by the LINGO-1 gene in human. LINGO-1 protein has been demonstrated to play a role in the structural plasticity and integrity of dopaminergic neurons as well as their survival in animal models of Parkinson's disease (PD). The LINGO family includes LINGO-1 to...
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