Article
Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component.
The Journal of cell biology - 3 Feb 2003
Myster Steven H, Cavallo Robert, Anderson Charles T, Fox Donald T, Peifer Mark
Abstract excerpt
Cadherin-catenin complexes, localized to adherens junctions, are essential for cell-cell adhesion. One means of regulating adhesion is through the juxtamembrane domain of the cadherin cytoplasmic tail. This region is the binding site for p120, leading to the hypothesis that p120 is a key regulator of cell adhesion. p120 has also been suggested to regulate the GTPase Rho and to regulate transcription via its...
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