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Article

The rs391957 variant cis-regulating oncogene GRP78 expression contributes to the risk of hepatocellular carcinoma.

Carcinogenesis - 1 Jun 2013

Zhu Xiao, Zhang Jinfang, Fan Wenguo, Wang Fang, Yao Hong, Wang Zifeng, Hou Shengping, Tian Yinghong, Fu Weiming, Xie Dan, Zhu Wei, Long Jun, Wu Leijie, Zheng Xuebao, Kung Hsiangfu, Zhou Keyuan, Lin Marie C M, Luo Hui, Li Dongpei

Abstract excerpt

Glucose-regulated protein 78 (GRP78) is one of the most important responders to disease-related stress. We assessed the association of the promoter polymorphisms of GRP78 with risk of hepatocellular carcinoma (HCC) and GRP78 expression in a Chinese population. We examined 1007 patients undergoing diagnostic HCC and 810 unrelated healthy controls. Mechanisms by which the GRP78 promoter polymorphism modulates HCC...

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PMID: 23416888
DOI: 10.1093/carcin/bgt061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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