Article
Polymorphisms of glucose-regulated protein 78 and clinical relevance of neuroblastoma: Risk and prognosis.
Journal of cancer research and therapeutics - 1 Jan 2000
Zhang Jiao, Wang Jiaxiang, Liu Qiuliang, Gao Jingyao, Wang Qi
Abstract excerpt
BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Glucose/regulated protein 78 (GRP78) is a stress-associated protein. It has been reported that overexpression of GRP78 occurs in various human cancers, and GRP78 polymorphisms have effect on the expression of GRP78 with possible function of predicting clinical outcome. Upregulation of GRP78 has been detected in NB. However,...
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