Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest China.

doi:10.1371/journal.pone.0066791

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest China.

PloS one - 1 Jan 2013

Zhang Dan, Zhou Bin, Li Yuan, Wang Mojin, Wang Cun, Zhou Zongguang, Sun Xiaofeng

Abstract excerpt

Glucose-regulated protein 78 (GRP78), an endoplasmic reticulum chaperone, up-regulation serves as an efficient mechanism to promote malignant transformation of colorectal cancer (CRC) and protect CRC cells against apoptosis. Recently, the analysis of GRP78 polymorphisms has already determined that GRP78 rs391957 polymorphism could predict clinical outcome in CRC patients. Thus, we tested whether GRP78...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Endoplasmic Reticulum Chaperone BiP

Share to Heat-Shock Proteins

Share to Linkage Disequilibrium

Share to Neoplasm Invasiveness

Share to Odds Ratio

Share to Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 23818965
DOI: 10.1371/journal.pone.0066791
PMCID: PMC3688565

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest China.PMID 23818965Read ↗

GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.Semantic proximity Read ↗

Polymorphisms of glucose-regulated protein 78 and clinical relevance of neuroblastoma: Risk and prognosis.Semantic proximity Read ↗

The 78 kDa glucose regulated protein (GRP78) as a potential treatment predictive biomarker and therapeutic target in colorectal cancer adjuvant chemotherapySemantic proximity Read ↗

The rs391957 variant cis-regulating oncogene GRP78 expression contributes to the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Targeting PERK and GRP78 in colorectal cancer: Genetic insights and novel therapeutic approaches.Semantic proximity Read ↗

Single nucleotide polymorphism of rs430397 in the fifth intron of GRP78 gene and clinical relevance of primary hepatocellular carcinoma in Han Chinese: risk and prognosis.Semantic proximity Read ↗

Clinic Correlation and Prognostic Value of P4HB and GRP78 Expression in Gastric CancerSemantic proximity Read ↗

Association between an 8q24 locus and the risk of colorectal cancer in Japanese.Semantic proximity Read ↗

Association between XRCC1 ARG399GLN and P53 ARG72PRO polymorphisms and the risk of gastric and colorectal cancer in Turkish population.Semantic proximity Read ↗

Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention.Semantic proximity Read ↗

Impaired fasting glucose, single-nucleotide polymorphisms, and risk for colorectal cancer in Koreans.Semantic proximity Read ↗

Genetic variants on chromosome 8q24 and colorectal neoplasia risk: a case-control study in China and a meta-analysis of the published literature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.