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Article

Hypoxia inducible factor-1alpha gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinoma.

Journal of surgical oncology - 1 Aug 2010

Hsiao Pei-Ching, Chen Mu-Kuan, Su Shih-Chi, Ueng Kwo-Chang, Chen Yi-Chen, Hsieh Yi-Hsien, Liu Yu-Fan, Tsai Hsiu-Ting, Yang Shun-Fa

Abstract excerpt

BACKGROUND AND OBJECTIVES: The aim of this study was to examine the potential associations of two hypoxia inducible factor-1alpha (HIF-1alpha) gene polymorphisms, C1772T and G1790A, with the susceptibility and clinicopathological status of hepatocellular carcinoma. METHODS: A total of 449 subjects, including 347 healthy controls and 102 patients with hepatocellular carcinoma, were recruited in this study and...

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Identifiers

PMID: 20648588
DOI: 10.1002/jso.21539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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