Article
No association between the haplotypic block in the 3' UTR of GRP78 and risk of hepatocellular carcinoma.
Hepato-gastroenterology - 1 Jan 2000
Zhu Xiao, Wang Jinlong, Wang Qian, Zhang Ying, Chen Lianzhou, Tian Linwei, Shen Hongzhuo, Lin Marie C M, Wang Min, Xie Dan, Kung Hsiangfu
Abstract excerpt
BACKGROUND/AIMS: Glucose-regulated protein 78 (GRP78), being a major chaperone, is implicated in the progression of hepatocellular carcinoma (HCC), and elevated GRP78 levels in tissues had been known to be related with poor prognosis in patients with HCC. In the present study, we investigated the possible association between the polymorphisms of haplotypic block in the 3' untranslated region (UTR) of GRP78 and...
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