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Article

The NAT2 tag SNP rs1495741 correlates with the susceptibility of antituberculosis drug-induced hepatotoxicity.

Pharmacogenetics and genomics - 1 Apr 2013

Ho Hsin-Tien, Wang Teng-Hsu, Hsiong Cheng-Huei, Perng Wann-Cherng, Wang Ning-Chi, Huang Tien-Yu, Jong Yuh-Jyh, Lu Po-Liang, Hu Oliver Yoa-Pu

Abstract excerpt

BACKGROUND: Earlier studies have demonstrated an association between N-acetyltransferase 2 (NAT2) catalytic activity and the genotype of a recently published tag single nucleotide polymorphism (SNP), rs1495741. There have been no reports on the relationship between the rs1495741 genotype and antituberculosis drug-induced hepatotoxicity (ATDIH) to date. OBJECTIVE: The aim of the present study was to determine the...

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PMID: 23407048
DOI: 10.1097/FPC.0b013e32835e95e1

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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