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Article

Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients

1 Jan 2018

Abstract excerpt

Background: Gene polymorphisms have been associated with drug-induced liver injury (DILI). This study aimed to elucidate the association between polymorphisms of NAT2, CYP2E1, GSTT1, GSTM1, and HLA genes with isoniazid plasma concentration and DILI. Methods: This study was a prospective cohort study recruiting adult newly diagnosed tuberculosis (TB) patients who met the inclusion criteria from the Public Health...

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Share to Chemotherapy-induced organ toxicity mitigation
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Identifiers

PMID: 30531039
DOI: 10.4103/ijmy.ijmy_143_18

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