Article
Macrophage migration inhibitory factor (MIF): genetic evidence for participation in early onset and early stage rheumatoid arthritis.
Cytokine - 1 Mar 2013
Llamas-Covarrubias M A, Valle Y, Bucala R, Navarro-Hernández R E, Palafox-Sánchez C A, Padilla-Gutiérrez J R, Parra-Rojas I, Bernard-Medina A G, Reyes-Castillo Z, Muñoz-Valle J F
Abstract excerpt
Macrophage migration inhibitory factor (MIF) is an upstream pro-inflammatory cytokine that is associated with the pathogenesis of autoimmune inflammatory diseases including rheumatoid arthritis (RA). Two polymorphisms in the upstream region exist in the MIF gene and are associated with RA susceptibility or severity in different populations. In this case-control study, we investigated whether MIF polymorphisms are...
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