Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico.

Molecular genetics & genomic medicine - 1 Jan 2020

Santoscoy-Ascencio Guillermo, Baños-Hernández Christian Johana, Navarro-Zarza José Eduardo, Hernández-Bello Jorge, Bucala Richard, López-Quintero Andres, Valdés-Alvarado Emmanuel, Parra-Rojas Isela, Illades-Aguiar Berenice, Muñoz-Valle José Francisco

Abstract excerpt

BACKGROUND: Macrophage migration inhibitory factor (MIF) is a cytokine capable of stimulating inflammatory cytokine and matrix metalloproteinase production from macrophages and synovial fibroblasts, which leads to persistent inflammation and bone degradation, two of the major pathological processes in rheumatoid arthritis (RA). The aim of this study was to evaluate the association of MIF promoter polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intramolecular Oxidoreductases

Share to Macrophage Migration-Inhibitory Factors

Share to Mexico

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 31701681
DOI: 10.1002/mgg3.1037
PMCID: PMC6978234

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico.PMID 31701681Read ↗

Associations between circulating macrophage migration inhibitory factor (MIF) levels and rheumatoid arthritis, and between MIF gene polymorphisms and disease susceptibility: a meta-analysis.Semantic proximity Read ↗

Macrophage migration inhibitory factor (MIF): genetic evidence for participation in early onset and early stage rheumatoid arthritis.Semantic proximity Read ↗

Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.Semantic proximity Read ↗

Macrophage migration inhibitory factor: association of -794 CATT5-8 and -173 G>C polymorphisms with TNF-α in systemic lupus erythematosus.Semantic proximity Read ↗

MIF functional polymorphisms (-794 CATT5-8 and -173 G>C) are associated with MIF serum levels, severity and progression in male multiple sclerosis from western Mexican population.Semantic proximity Read ↗

Macrophage migration inhibitory factor may play a protective role in osteoarthritisSemantic proximity Read ↗

Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor.Semantic proximity Read ↗

Association of MIF-173G/C and MBL2 codon 54 gene polymorphisms with rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus.Semantic proximity Read ↗

Circulating macrophage migration inhibitory factor levels and its polymorphisms in systemic lupus erythematosus: A meta-analysis.Semantic proximity Read ↗

Genotyping Two Promoter Polymorphisms in the MIF Gene: A -794 CATT5-8 Microsatellite Repeat and a -173 G/C SNP.Semantic proximity Read ↗

Macrophage migration inhibitory factor polymorphisms are a potential susceptibility marker in systemic sclerosis from southern Mexican population: association with MIF mRNA expression and cytokine profileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.