Article
Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor.
Arthritis and rheumatism - 1 Oct 2005
Radstake Timothy R D J, Sweep Fred C G J, Welsing Paco, Franke Barbara, Vermeulen Sita H H M, Geurts-Moespot Anneke, Calandra Thierry, Donn Rachelle, van Riel Piet L C M
Abstract excerpt
OBJECTIVE: To study whether genetic variants of macrophage migration inhibitory factor (MIF), the MIF -173G>C and CATT(5-8) alleles, are associated with disease severity and levels of circulating MIF in patients with rheumatoid arthritis (RA). METHODS: Genotyping was performed in patients with early RA and in healthy controls. Demographic data, disease activity, and outcome measurements were compared between...
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