Article
Macrophage migration inhibitory factor gene: influence on rheumatoid arthritis susceptibility.
Human immunology - 1 Sept 2007
Martínez Alfonso, Orozco Gisela, Varadé Jezabel, Sánchez López Marta, Pascual Dora, Balsa Alejandro, García Antonio, de la Concha Emilio G, Fernández-Gutiérrez Benjamín, Martín Javier, Urcelay Elena
Abstract excerpt
The macrophage inhibitory factor (MIF) is a cytokine that has been implicated in several inflammatory and autoimmune diseases, including rheumatoid arthritis, systemic lupus, glomerulonephritis, and multiple sclerosis. In rheumatoid arthritis (RA), results ranging from lack of association of MIF polymorphisms with RA, to involvement in either severity or susceptibility to the disease have been reported in the...
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