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Article

The Hallmarks of Cancer as Eco-Evolutionary Processes

2 Apr 2025

Abstract excerpt

Abstract The “Hallmarks of Cancer” represent characteristics of neoplastic cells. Hanahan and Weinberg noted that the acquisition of these hallmarks mimics Darwinian evolution. In this study, we deconstruct the hallmarks “color wheel” into linear, parallel, and interlinked stages: cancer initiation, evolving evolvability, niche construction, adaptations for safety, and emergent phenomenon. During carcinogenesis,...

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PMID: 40170539
DOI: 10.1158/2159-8290.cd-24-0861

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