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Article

The association of the placental MTHFR 3'-UTR polymorphisms, promoter methylation, and MTHFR expression with preeclampsia.

Journal of cellular biochemistry - 1 Feb 2018

Mohammadpour-Gharehbagh Abbas, Teimoori Batool, Narooei-Nejad Mehrnaz, Mehrabani Mehrnaz, Saravani Ramin, Salimi Saeedeh

Abstract excerpt

Preeclampsia (PE) is a pregnancy specific complication arises in presence of the placenta and disappears immediately after delivery. Therefore, the aim of the present study was to investigate the possible effects of the placental 3'-UTR rs1537514C>G and rs4846049C>A polymorphisms and DNA methylation of the MTHFR gene on the MTHFR mRNA expression. The placenta of 74 PE pregnant women and 75 normotensive pregnant...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Placenta

Share to Pre-Eclampsia

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 28722783
DOI: 10.1002/jcb.26290

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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