Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing.

Experimental and molecular pathology - 1 Oct 2015

Putra Juan, de Abreu Francine B, Peterson Jason D, Pipas J Marc, Mody Kabir, Amos Christopher I, Tsongalis Gregory J, Suriawinata Arief A

Abstract excerpt

Cholangiocarcinoma is a heterogeneous malignant process, which is further classified into intrahepatic cholangiocarcinoma (ICC) and extrahepatic cholangiocarcinoma (ECC). The poor prognosis of the disease is partly due to the lack of understanding of the disease mechanism. Multiple gene alterations identified by various molecular techniques have been described recently. As a result, multiple targeted therapies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Cholangiocarcinoma

Share to Gene Expression Profiling

Share to High-Throughput Nucleotide Sequencing

Share to Real-Time Polymerase Chain Reaction

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 26189129
DOI: 10.1016/j.yexmp.2015.07.005
PMCID: PMC4591249

Genes

BRAF
IDH1
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing.PMID 26189129Read ↗

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for InterventionSemantic proximity Read ↗

Molecular Profile of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience.Semantic proximity Read ↗

Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications.Semantic proximity Read ↗

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experienceSemantic proximity Read ↗

Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.Semantic proximity Read ↗

Molecular profiling in cholangiocarcinoma: A practical guide to next-generation sequencing.Semantic proximity Read ↗

New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation SequencingSemantic proximity Read ↗

Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western PatientsSemantic proximity Read ↗

Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions.Semantic proximity Read ↗

Practical considerations in screening for genetic alterations in cholangiocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.