Article
Molecular Pathogenesis of Cholangiocarcinoma: Implications for Disease Classification and Therapy.
Oncology (Williston Park, N.Y.) - 10 Aug 2022
Kabbara Khaled W, Cannon Timothy, Winer Arthur, Wadlow Raymond C
Abstract excerpt
Cholangiocarcinomas are an aggressive group of heterogeneous malignancies that affect over 210,000 individuals globally each year. Their incidence is rising, particularly in Western countries. Traditionally, cholangiocarcinomas are classified based on anatomic location of the tumor and are treated with similar cytotoxic chemotherapy despite significant molecular and genomic differences. With the rise of genetic...
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