Article

The memory B cell response to influenza vaccination is impaired in older persons

2021-03-04

Abstract excerpt

Influenza imparts an age-related increase in mortality and morbidity. The most effective countermeasure is vaccination; however, vaccines offer modest protection in older adults. To investigate how ageing impacts the memory B cell response we tracked haemagglutinin specific B cells by indexed flow sorting and single cell RNA sequencing in twenty healthy adults administered the trivalent influenza vaccine. We found...

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Literature Corpus work: a2a9dec3-d229-569d-b1e9-d001de125d09
DOI: 10.1101/2021.03.04.433942

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