Article
HFE H63D mutation frequency shows an increase in Turkish women with breast cancer.
BMC cancer - 19 Feb 2006
Gunel-Ozcan Aysen, Alyilmaz-Bekmez Sibel, Guler Emine Nilufer, Guc Dicle
Abstract excerpt
BACKGROUND: The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular malignancies. This study was performed to compare frequencies of HFE C282Y and H63D variants in Turkish women with breast cancer and healthy controls. METHODS: Archived DNA samples of...
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