Article
Plasma ferritin levels, HFE polymorphisms, and risk of pancreatic cancer among Chinese Han population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014
Zhao Zhiming, Li Chenggang, Hu Minggeng, Li Jidong, Liu Rong
Abstract excerpt
The etiology of pancreatic cancer (PC) remains poorly understood. High iron levels can increase the formation of noxious oxygen radicals, which are thought to promote carcinogenesis. The aim of this study was to determine whether iron biomarkers and HFE genotypes, which influence iron regulation, constitute risk factors for PC. A case-control study was conducted to examine plasma ferritin levels (n = 1,000 cases;...
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